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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1L All Species: 35.76
Human Site: Y118 Identified Species: 49.17
UniProt: Q96HE7 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HE7 NP_055399.1 468 54393 Y118 D G I K S A S Y K Y S E E A N
Chimpanzee Pan troglodytes XP_509950 468 54427 Y118 D G I K S A S Y K Y S E E A N
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 Y118 D G I K S A S Y K Y S E E A N
Dog Lupus familis XP_547813 468 54343 Y118 D G I K S A S Y K Y S E V A N
Cat Felis silvestris
Mouse Mus musculus Q8R180 464 54066 Y118 D G I K S A S Y K Y S E E A N
Rat Rattus norvegicus Q8R4A1 464 54000 Y118 D G I K S A S Y K Y S K E A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515503 465 53870 Y115 D G I K S S S Y K Y S E E A N
Chicken Gallus gallus XP_421473 463 52908 Y116 D G I R S A G Y K Y S E E A N
Frog Xenopus laevis Q6DD71 465 53720 K114 G F K P P G F K Y T E E A N H
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 Y110 E G L K S S S Y K Y S E K A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 E127 Q G I K D K G E H K E K A A F
Honey Bee Apis mellifera XP_623933 471 55049 L122 D G L K G D I L R N V H F N E
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 V112 G L R R R N A V N M E A A A V
Sea Urchin Strong. purpuratus XP_796844 897 101920 N535 C G L K E E S N E N K Y S S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 V141 E P F K K P F V P G L P S D D
Baker's Yeast Sacchar. cerevisiae Q03103 563 65014 E123 L P E Y W Q P E I L G S F N N
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 A111 D I P E V W R A K E L G K L E
Conservation
Percent
Protein Identity: 100 99.5 98.7 96.3 N.A. 91.8 91.4 N.A. 84.6 77.7 70.9 62.1 N.A. 46.1 48.4 41.4 29.3
Protein Similarity: 100 99.5 99.3 97.8 N.A. 95.9 95.7 N.A. 90.1 85.4 83.9 75.4 N.A. 64.1 65.6 60.8 37.6
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 93.3 86.6 6.6 66.6 N.A. 26.6 20 6.6 20
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 100 93.3 13.3 100 N.A. 33.3 33.3 20 46.6
Percent
Protein Identity: N.A. N.A. N.A. 37.9 22.5 22.1
Protein Similarity: N.A. N.A. N.A. 55.6 41.2 38
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 20 6.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 42 6 6 0 0 0 6 18 65 0 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 59 0 0 0 6 6 0 0 0 0 0 0 0 6 12 % D
% Glu: 12 0 6 6 6 6 0 12 6 6 18 53 42 0 12 % E
% Phe: 0 6 6 0 0 0 12 0 0 0 0 0 12 0 6 % F
% Gly: 12 71 0 0 6 6 12 0 0 6 6 6 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 6 0 0 6 0 0 6 % H
% Ile: 0 6 53 0 0 0 6 0 6 0 0 0 0 0 0 % I
% Lys: 0 0 6 71 6 6 0 6 59 6 6 12 12 0 0 % K
% Leu: 6 6 18 0 0 0 0 6 0 6 12 0 0 6 0 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 6 0 6 6 12 0 0 0 18 53 % N
% Pro: 0 12 6 6 6 6 6 0 6 0 0 6 0 0 0 % P
% Gln: 6 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 6 12 6 0 6 0 6 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 53 12 53 0 0 0 53 6 12 6 6 % S
% Thr: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % T
% Val: 0 0 0 0 6 0 0 12 0 0 6 0 6 0 6 % V
% Trp: 0 0 0 0 6 6 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 0 53 6 53 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _